Mary Orr, a retired Navy Chief Hospital Corpsman (HMC Mary Coppola) and a former acupuncturist, was diagnosed with Parkinson’s Disease in 2005 at the age of 46. A case of the flu in 2008 changed her mild Parkinson’s to severe, forcing her to close her acupuncture practice and go on disability. After 8 years of trying all existing Parkinson’s medications, only Sinemet worked for Mary. Now even the Sinemet is no longer working well. Plus, she is not a candidate for Deep Brain Stimulation. Her once vibrant and active life has been reduced to 4 separate one hour or less blocks of time throughout the day in which she must eat, shower, walk, exercise, and attempt activities of daily living. In essence, she is confined to the apartment.
At this time the Sinemet has become unpredictable. When it is not working (which is most of the day), she is either writhing with pain and/or unable to walk, talk, or move. At this point, Stem Cell therapy using her own stem cells is her best hope to regain functionality. Unfortunately, this is very expensive. Mary’s whole life has been about helping others; now she needs help. Through the long ordeal over the years, Mary has remained steadfast in her hope for better quality of life. She often has said to others and believes for herself “Miracles do happen.”
October 17, 2017
Here we are 1 month later. Mary still struggles with sleep. She had a UTI about a month ago, and the antibiotics caused problems with her medications, resulting in increased, constant chronic pain throughout her whole body. Her insomnia has gotten worse again after seeing some slight improvement before the antibiotics.
Thanks for all the prayers and support. We greatly appreciate it.
Michael & Mary Orr
September 21, 2017
Hi Everyone. Sorry for taking so long with updating. Mary is currently fighting a UTI that started up last Wednesday, the 13th. We saw the NP in the Doctor’s office, and she prescribed Bactrim, especially since Mary can’t take Cipro due to bad reactions to it in the past.
In doing some digging on the internet, we found that Bactrim inhibits an enzyme that converts folate into a methylated version. In essence it slows down the methylation process, which is not good since Mary is already a slow methylator as it is. We have noticed a decrease in the effectiveness of the Sinemet (less on time) and increased dyskinesias (wild, involuntary movements) as a result of taking the necessary antibiotics.
Before this, she was starting to see minor improvements. She was able to roll over in bed and get up to go to the bathroom unassisted in the middle of the night. Hopefully these and other improvements will be regained after the course of antibiotics is over.
This whole process has been challenging, but we are hopeful that Mary’s health will improve.
Many Blessings to All
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May 28, 2019
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May 27, 2017
Thank you for your service, God Bless you and your family.
June 1, 2017
We're with you! God bless!
Rob Rodriguez & family
June 3, 2017
Thank you for your service. I'm praying for continued strength and a better quality of life.